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Also, the indole Main is substituted at R3 using a carbonyl team which can be also bonded to the napthalene moeity. Napthalene is often a bicyclic construction of two fused benzene rings. This carbonyl bridge of JWH-018 classifies it to be a ketone. JWH-018 can be an analog of THJ-018, wherein the Main indazole composition is substituted by having
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